HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxothiazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Rhodanine | HCID 1201546 | — |
| Reactant | 5-Formyl-2,3-dihydroxybenzonitrile | HCID 15292583 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxothiazolidin-4-one | HCID 53780783 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A solution containing 0.61 g of rhodanine, 0.72 g of 3,4-dihydroxy-5-cyanobenzaldehyde and 0.1 ml of piperidine in 10 ml of acetic acid was heated for 4 h at 100° C. The product was filtered and washed with 2-propanol. Yield 0.35 g, mp>350° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06121303 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-b4754c6df49744ab954cabee13a76af9 |
| Source note | uspto-grants-2000_09 |