HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11304555, compound → HCID 11381753, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11304555 | HCID 11304555 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 11381753 | HCID 11381753 | — |
Reaction Steps
A mixture of benzyl-[3-(1H-indol-3-yl)-propyl]-[2-(2-methoxy-phenoxy)-ethyl]amine (2 g, 4.7 mmol) and 5% palladium on carbon in ethanol was hydrogenated for 20 hours. The catalyst was filtered off and the solvent removed under vacuum. Chromato-graphy (ethyl acetate-hexanes-methanol-ammonia hydroxide: 4/4/1/1) affored 0.79 g (52%) of product as a white solid: mp 101-102° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06121307 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-aac4d43862b14065b1fc131034107a60 |
| Source note | uspto-grants-2000_09 |