Acetic Anhydride → HCID 53849991, compound

HRID 1954271Notes

Reaction equation

HRID 1954271 reaction equation
[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8]3[C:13](=[C:14]([C:15]4[CH:20]=[C:19]([CH:21]([CH3:23])[CH3:22])[C:18]([OH:24])=[C:17]([CH:25]([CH3:27])[CH3:26])[CH:16]=4)[C:4]=2[C:3]=1[CH3:28])[CH:12]=[CH:11][CH:10]=[CH:9]3.[C:29](OC(=O)C)(=[O:31])[CH3:30]>N1C=CC=CC=1>[CH3:1][C:2]1[S:6][C:5]2[CH:7]=[C:8]3[C:13](=[C:14]([C:15]4[CH:20]=[C:19]([CH:21]([CH3:23])[CH3:22])[C:18]([O:24][C:29](=[O:31])[CH3:30])=[C:17]([CH:25]([CH3:27])[CH3:26])[CH:16]=4)[C:4]=2[C:3]=1[CH3:28])[CH:12]=[CH:11][CH:10]=[CH:9]3

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 18430727HCID 18430727, compound

Product 1

HCID 53849991HCID 53849991, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Using 4-(2,3-dimethyl-naphtho[2,3-b]thiophen-4-yl)-2,6-diisopropyl-phenol (5.0 g, 13.7 mmol), acetic anhydride (1.68 mL, 17.8 mmol), and pyridine (85 mL) the title compound was prepared according to the procedure in Example 2, step 3 to give 5.37 g (91%) as a white solid, mp 243-245° C.; NMR (DMSO-d6) δ 8.49 (s, 1 H), 7.98 (d, 1 H), 7.49-7.39 (m, 3 H), 7.16 (s, 2 H), 3.01 (septet, 2 H), 2.43 (s, 3 H), 2.41 (s, 3 H), 1.56 (s, 3 H), 1.16 (d, 12 H). MS(EI), [M+] 430; Anal. Calc. for C28H30O2S: C, 78.10, H, 7.02, N, 0.00. Found: C, 77.95, H, 7.04, N, 0.07.

Sources & evidence

ORD record
ord-d5377605628a40ec99390d76547b8226
Source dataset
uspto-grants-2000_09
Patent number
US06121271

Reaction notes

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