Tin tetrachloride → HCID 18430717, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure in Example 1, step 4, using 3,5-diethyl-4-methoxybenzoic acid (9.45 g, 45.5 mmol), oxalyl chloride (4.35 mL, 50.0 mmol), N,N-DMF (2 drops), tin(IV) chloride (5.85 mL, 50.0 mmol) and 2-benzyl-4,5-dimethylthiophene (11.0 g, 54.6 mmol) to give 17.67 g (99%) of the title compound. 1H NMR δ 1.13 (t, 6 H), 1.83 (s, 3 H), 2.27 (s, 3 H), 2.64 (q, 4 H), 3.73 (s, 3 H), 3.85 (s, 2 H), 7.04 (d, 2 H), 7.12-7.24 (m, 3 H), 7.43 (s, 2 H).

Provenance & Evidence