反应详情

The title compound was prepared according to the procedure in Example 1, step 5, using (2-benzyl-4,5-dimethylthiophen-3-yl)-(3,5-diethyl-4-methoxy-phenyl)-methanone (17.67 g, 45.0 mmol) and boron tribromide (12.8 mL, 0.135 mol) to give 16.63 g, of the title compound. 1H NMR (DMSO-d6) δ 1.15 (t, 6 H), 1.61 (s, 3 H), 2.40 (s, 3 H), 2.59-2.73 (m, 4 H), 6.86 (s, 2 H), 7.32 (ddd, 1 H), 7.42 (ddd, 1 H), 7.47 (d, 1 H), 7.93 (d, 1 H), 8.31 (s, 1 H), 8.41 (s, 1 H). mass spectrum (+ESI) m/z 360 (M+).

1. customThe title compound was prepared
2. customto give 16.63 g