Ethyl chloroformate → Diethyl 2-amino-6-[(ethoxycarbonyloxy-carbamoyl)-methyl]-azulene-1,3-dicarboxylate

HRID 1954352Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1954352
[NH2:1][C:2]1[C:11]([C:12]([O:14][CH2:15][CH3:16])=[O:13])=[C:10]2[C:4](=[CH:5][CH:6]=[C:7]([CH2:17][C:18](=[O:21])[NH:19][OH:20])[CH:8]=[CH:9]2)[C:3]=1[C:22]([O:24][CH2:25][CH3:26])=[O:23].Cl[C:28]([O:30][CH2:31][CH3:32])=[O:29]>>[NH2:1][C:2]1[C:11]([C:12]([O:14][CH2:15][CH3:16])=[O:13])=[C:10]2[C:4](=[CH:5][CH:6]=[C:7]([CH2:17][C:18](=[O:21])[NH:19][O:20][C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH:8]=[CH:9]2)[C:3]=1[C:22]([O:24][CH2:25][CH3:26])=[O:23]

Komponenten

3

Edukt 2

HCID 10928Ethyl chloroformateHCID 9863689Diethyl 2-amino-6-[(hydroxycarbamoyl)-methyl]-azulene-1,3-dicarboxylate

Produkt 1

HCID 23296747Diethyl 2-amino-6-[(ethoxycarbonyloxy-carbamoyl)-methyl]-azulene-1,3-dicarboxylateAusbeute 47 %

Versuchsvorschrift

In an analogous manner to that described in Example 12, from diethyl 2-amino-6-[(hydroxycarbamoyl)-methyl]-azulene-1,3-dicarboxylate and ethyl chloroformate the title compound is obtained in 47% yield as an oil.

Quellen und Nachweise

ORD-Eintrag
ord-429e80104c6a40ea9279c57c34818960
Quelldatensatz
uspto-grants-2000_09
Patentnummer
US06121322

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