HCID 23296404, compound → HCID 23296566, compound

HRID 1954355Notes

Reaction equation

HRID 1954355 reaction equation
[CH2:1]([O:3][C:4]([CH2:6][N:7]1[C:11]2[CH:12]=[CH:13][C:14]([N:16]([S:22]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)(=[O:24])=[O:23])[CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])=[CH:15][C:10]=2[N:9]=[C:8]1[CH2:31][O:32][C:33]1[CH:38]=[CH:37][C:36]([C:39]#[N:40])=[CH:35][CH:34]=1)=[O:5])[CH3:2].Cl.C(=O)([O-])[O-].[NH4+:46].[NH4+]>C(O)C>[CH2:1]([O:3][C:4]([CH2:6][N:7]1[C:11]2[CH:12]=[CH:13][C:14]([N:16]([S:22]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)(=[O:24])=[O:23])[CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])=[CH:15][C:10]=2[N:9]=[C:8]1[CH2:31][O:32][C:33]1[CH:34]=[CH:35][C:36]([C:39](=[NH:46])[NH2:40])=[CH:37][CH:38]=1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 23296404HCID 23296404, compoundHCID 86755731HCID 86755731, compound

Product 1

HCID 23296566HCID 23296566, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1e from 1-ethoxycarbonylmethyl-2-[(4-cyanophenyl)-oxymethyl]-5-[N-(2-dimethylaminoethyl)-benzenesulphonylamino]-benzimidazole and hydrochloric acid/ammonium carbonate in ethanol.

Sources & evidence

ORD record
ord-350c2692eb9e4152b6e69058e9846212
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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