Sodium Hydroxide → HCID 23296456, compound

HRID 1954364Notes

Reaction equation

HRID 1954364 reaction equation
[CH:1]1([N:4]2[C:8]3[CH:9]=[CH:10][C:11]([N:13]([S:20]([C:23]4[CH:24]=[CH:25][CH:26]=[C:27]5[C:32]=4[N:31]=[CH:30][CH:29]=[CH:28]5)(=[O:22])=[O:21])[CH2:14][C:15]([O:17]CC)=[O:16])=[CH:12][C:7]=3[N:6]=[C:5]2[CH2:33][CH2:34][C:35]2[CH:40]=[CH:39][C:38]([C:41](=[NH:43])[NH2:42])=[CH:37][CH:36]=2)[CH2:3][CH2:2]1.[OH-].[Na+]>>[CH:1]1([N:4]2[C:8]3[CH:9]=[CH:10][C:11]([N:13]([S:20]([C:23]4[CH:24]=[CH:25][CH:26]=[C:27]5[C:32]=4[N:31]=[CH:30][CH:29]=[CH:28]5)(=[O:21])=[O:22])[CH2:14][C:15]([OH:17])=[O:16])=[CH:12][C:7]=3[N:6]=[C:5]2[CH2:33][CH2:34][C:35]2[CH:40]=[CH:39][C:38]([C:41](=[NH:42])[NH2:43])=[CH:37][CH:36]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23296643HCID 23296643, compound

Product 1

HCID 23296456HCID 23296456, compound

Procedure

Prepared analogously to Example 3 from 1-cyclopropyl-2-[2-(4-amidinophenyl)-ethyl]-5-[N-(ethoxycarbonylmethyl)-quinoline-8-sulphonylamino]-benzimidazole and sodium hydroxide solution.

Sources & evidence

ORD record
ord-2a7c2c95410f41adb5b57cf6b3c0ec7b
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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