Sodium Hydroxide → HCID 23296431, compound

HRID 1954378Notes

Reaction equation

HRID 1954378 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([S:18]([C:21]3[CH:22]=[CH:23][CH:24]=[C:25]4[C:30]=3[N:29]=[CH:28][CH:27]=[CH:26]4)(=[O:20])=[O:19])[CH2:12][C:13]([O:15]CC)=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:31][NH:32][CH2:33][C:34]1[CH:39]=[CH:38][C:37]([C:40](=[NH:42])[NH2:41])=[CH:36][CH:35]=1.[OH-].[Na+]>>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([S:18]([C:21]3[CH:22]=[CH:23][CH:24]=[C:25]4[C:30]=3[N:29]=[CH:28][CH:27]=[CH:26]4)(=[O:20])=[O:19])[CH2:12][C:13]([OH:15])=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:31][NH:32][CH2:33][C:34]1[CH:35]=[CH:36][C:37]([C:40](=[NH:41])[NH2:42])=[CH:38][CH:39]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23296504HCID 23296504, compound

Product 1

HCID 23296431HCID 23296431, compound

Procedure

Prepared analogously to Example 3 from 1-methyl-2-[N-(4-amidinobenzyl)-aminomethyl]-5-[N-(ethoxycarbonylmethyl)-quinoline-8-sulphonylamino]-benzimidazole and sodium hydroxide solution.

Sources & evidence

ORD record
ord-ae73daa300c24f7c86a6ccb6a7b0a68b
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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