Sodium Hydroxide → HCID 23296502, compound

HRID 1954382Notes

Reaction equation

HRID 1954382 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([S:18]([CH2:21][CH2:22][CH2:23][CH3:24])(=[O:20])=[O:19])[CH2:12][C:13]([O:15]CC)=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:25][NH:26][C:27]1[CH:32]=[CH:31][C:30]([C:33](=[NH:35])[NH2:34])=[CH:29][CH:28]=1.[OH-].[Na+]>>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([S:18]([CH2:21][CH2:22][CH2:23][CH3:24])(=[O:20])=[O:19])[CH2:12][C:13]([OH:15])=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:25][NH:26][C:27]1[CH:28]=[CH:29][C:30]([C:33](=[NH:34])[NH2:35])=[CH:31][CH:32]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23296644HCID 23296644, compound

Product 1

HCID 23296502HCID 23296502, compound

Procedure

Prepared analogously to Example 3 from 1-methyl-2-[N-(4-amidinophenyl)-aminomethyl]-5-[N-(ethoxycarbonylmethyl)-n-butanesulphonylamino]-benzimidazole and sodium hydroxide solution.

Sources & evidence

ORD record
ord-c12d624a243142dcb37e1e3eb7741a05
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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