Sodium Hydroxide → HCID 23296613, compound

HRID 1954384Notes

Reaction equation

HRID 1954384 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)=[O:19])[CH2:12][C:13]([O:15]CC)=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:26][NH:27][C:28]1[CH:33]=[CH:32][C:31]([C:34](=[NH:36])[NH2:35])=[CH:30][CH:29]=1.[OH-].[Na+]>>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)=[O:19])[CH2:12][C:13]([OH:15])=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:26][NH:27][C:28]1[CH:29]=[CH:30][C:31]([C:34](=[NH:35])[NH2:36])=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 54162022HCID 54162022, compound

Product 1

HCID 23296613HCID 23296613, compound

Procedure

Prepared analogously to Example 3 from 1-methyl-2-[N-(4-amidinophenyl)-aminomethyl]-5-[N-(ethoxycarbonylmethyl)-pyridin-2-yl-carbonylamino]-benzimidazole and sodium hydroxide solution.

Sources & evidence

ORD record
ord-b8975a5cdc694aa09c39b19cf641d12e
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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