Potassium Nitrate → HCID 23296614, compound

HRID 1954389Notes

Reaction equation

HRID 1954389 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH2:11][CH2:12][C:13]1[CH:20]=[CH:19][C:16]([C:17]#[N:18])=[CH:15][CH:14]=1.[N+:21]([O-])([O-:23])=[O:22].[K+]>S(=O)(=O)(O)O>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([N+:21]([O-:23])=[O:22])=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH2:11][CH2:12][C:13]1[CH:14]=[CH:15][C:16]([C:17]#[N:18])=[CH:19][CH:20]=1

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 23296415HCID 23296415, compound

Product 1

HCID 23296614HCID 23296614, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Conditions

Temperature
2 °C

Procedure

Within 2 hours 1.7 g (6.53 mmol) of 4-[2-(1-methyl-indol-2-yl)ethyl]benzonitrile is dissolved in 20 ml conc. sulphuric acid at 15° C. and then cooled to 2° C. Then 0.66 g (6.53 mmol) of potassium nitrate are added batchwise (temperature rise to about 10° C.). The mixture is stirred for a further 30 minutes at 2-5° C. and then poured onto ice. The yellowish precipitate formed is filtered off and washed with water.

Workup

  1. additionpoured onto ice
  2. customThe yellowish precipitate formed
  3. filtrationis filtered off
  4. washwashed with water

Sources & evidence

ORD record
ord-8cbb750bedee41b59ed9df6abada1f36
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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