Sodium Hydroxide → HCID 23296402, compound

HRID 1954394Notes

Reaction equation

HRID 1954394 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([N:11]([S:18]([C:21]3[CH:22]=[CH:23][CH:24]=[C:25]4[C:30]=3[N:29]=[CH:28][CH:27]=[CH:26]4)(=[O:20])=[O:19])[CH2:12][C:13]([O:15]CC)=[O:14])=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH2:31][NH:32][C:33]1[CH:38]=[CH:37][C:36]([C:39](=[NH:41])[NH2:40])=[CH:35][CH:34]=1.[OH-].[Na+]>>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([N:11]([S:18]([C:21]3[CH:22]=[CH:23][CH:24]=[C:25]4[C:30]=3[N:29]=[CH:28][CH:27]=[CH:26]4)(=[O:20])=[O:19])[CH2:12][C:13]([OH:15])=[O:14])=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH2:31][NH:32][C:33]1[CH:34]=[CH:35][C:36]([C:39](=[NH:40])[NH2:41])=[CH:37][CH:38]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23296570HCID 23296570, compound

Product 1

HCID 23296402HCID 23296402, compound

Procedure

Prepared analogously to Example 3 from 1-methyl-2-[N-(4-amidinophenyl)-aminomethyl]-5-[N-(ethoxycarbonylmethyl)-quinoline-8-sulphonylamino]-indole and sodium hydroxide solution.

Sources & evidence

ORD record
ord-d534fd6182db4d5babc08de7842fc1c2
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

Loading…