Sodium Hydroxide → HCID 23296477, compound

HRID 1954402Notes

Reaction equation

[C:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][C:12]2[CH:21]=[C:20]([CH3:22])[C:19]3[C:14](=[CH:15][C:16]([N:23]([S:30]([C:33]4[CH:34]=[CH:35][CH:36]=[C:37]5[C:42]=4[N:41]=[CH:40][CH:39]=[CH:38]5)(=[O:32])=[O:31])[CH2:24][C:25]([O:27]CC)=[O:26])=[CH:17][CH:18]=3)[N:13]=2)=[CH:6][CH:5]=1)(=[NH:3])[NH2:2].[OH-].[Na+]>>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][C:12]2[CH:21]=[C:20]([CH3:22])[C:19]3[C:14](=[CH:15][C:16]([N:23]([S:30]([C:33]4[CH:34]=[CH:35][CH:36]=[C:37]5[C:42]=4[N:41]=[CH:40][CH:39]=[CH:38]5)(=[O:32])=[O:31])[CH2:24][C:25]([OH:27])=[O:26])=[CH:17][CH:18]=3)[N:13]=2)=[CH:6][CH:5]=1)(=[NH:2])[NH2:3]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 23296446HCID 23296446, compound

Product 1

HCID 23296477HCID 23296477, compound

Procedure

Prepared analogously to Example 3 from 2-[(4-amidinophenyl)-oxymethyl]-4-methyl-7-[N-(ethoxycarbonylmethyl)-quinoline-8-sulphonylamino]-quinoline and sodium hydroxide solution.

Sources & evidence

ORD record: ord-27da34282d754937bcdc43679f0da40a
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06121308

Reaction notes

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