Benzoyl chloride → HCID 141596224, compound

HRID 1954410Notes

Reaction equation

[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([S:19]([C:22]3[CH:23]=[CH:24][CH:25]=[C:26]4[C:31]=3[N:30]=[CH:29][CH:28]=[CH:27]4)(=[O:21])=[O:20])[CH2:12][C:13]([O:15][CH2:16][CH2:17][CH3:18])=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:32][NH:33][C:34]1[CH:39]=[CH:38][C:37]([C:40](=[NH:42])[NH2:41])=[CH:36][CH:35]=1.[C:43](Cl)(=[O:50])[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1>>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N:11]([S:19]([C:22]3[CH:23]=[CH:24][CH:25]=[C:26]4[C:31]=3[N:30]=[CH:29][CH:28]=[CH:27]4)(=[O:21])=[O:20])[CH2:12][C:13]([O:15][CH2:16][CH2:17][CH3:18])=[O:14])=[CH:10][C:5]=2[N:4]=[C:3]1[CH2:32][NH:33][C:34]1[CH:35]=[CH:36][C:37]([C:40](=[NH:41])[NH:42][C:43](=[O:50])[C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)=[CH:38][CH:39]=1

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 23296560HCID 23296560, compound

Product 1

HCID 141596224HCID 141596224, compound

Procedure

Prepared analogously to Example 31 from 1-methyl-2-[N-(4-amidino-phenyl)-aminomethyl]-5-[N-(n-propyloxycarbonylmethyl)-quinoline-8-sulphonylamino]-benzimidazole and benzoyl chloride.

Sources & evidence

ORD record: ord-98f814a19ca84b48934bee8e2fe1cc94
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06121308

Reaction notes

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