Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,3-Dibromopropane | HCID 8001 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Phthalimide | HCID 6809 | — |
Reaction Steps
A mixture of N-hydroxyphthalimide (100 mmol) and 1,3-dibromopropane (100 mmol) in dry DMF and triethyl amine (110 mmol) is stirred at 20-75° C. for 1-10 hours. After filtration, the mixture is evaporated to dryness under reduced pressure. The residue is purified by silica gel chromatography to give N-[(3-bromopropyl)oxy)]phthalimide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06121433 |
|---|
| Source dataset | uspto-grants-2000_09 |
|---|
| ORD ID | ord-be6fe6e6ce6f45939980df8a46eaa73e |
|---|
| Source note | uspto-grants-2000_09 |
|---|
