HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Dimethylamino)benzoic acid → 4-(Dimethylamino)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Dimethylamino)benzoic acid | HCID 12092 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(Dimethylamino)benzoyl chloride | HCID 4400782 | 78% |
Reaction Steps
4-Dimethylaminobenzoic acid (250 g, 1.51 moles) was suspended in 2 L of ethyl acetate and thionyl chloride (359.3 g, 3.02 moles) was added. After the completion, the solvent was evaporated. Crystallization from ethyl acetate gave 216 g of 4-dimethylaminobenzoyl chloride (78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06123928 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-3e283784c5244d3e8ca04569ded167bf |
| Source note | uspto-grants-2000_09 |