tert-Butyl bromoacetate → HCID 64578544, compound

HRID 1954683Notes

Reaction equation

HRID 1954683 reaction equation
Br[CH2:2][C:3]([O:5][C:6]([CH3:9])([CH3:8])[CH3:7])=[O:4].Cl.[NH2:11][CH2:12][CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[NH:11]([CH2:12][CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:2][C:3]([O:5][C:6]([CH3:9])([CH3:8])[CH3:7])=[O:4]

Participants

3

Reactant 2

HCID 79177tert-Butyl bromoacetateHCID 126496614-Aminobutyrate ethyl hydrochloride

Product 1

HCID 64578544HCID 64578544, compoundYield 55%

Procedure

By a method substantially equivalent to that described in Example 2-A; 13.6 g (55%) of N(CH2CH2CH2COOEt)Gly-O-t-Bu were prepared from t-butyl bromoacetate and ethyl 4-amino-butyrate hydrochloride.

Sources & evidence

ORD record
ord-a0393a6c610b4529b8aeb5bc12685548
Source dataset
uspto-grants-2000_09
Patent number
US06124277

Reaction notes

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