Oxalic Acid → HCID 70069774, compound

HRID 1954691Notes

Reaction equation

HRID 1954691 reaction equation
[OH:1][C:2]([C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)[CH2:3][CH2:4][C:5]([C:22]1[CH:27]=[CH:26][C:25]([OH:28])=[C:24]([CH2:29][N:30]2[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]2)[CH:23]=1)([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][N:15]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[CH:8]=1)[CH3:6].[C:49]([OH:54])(=[O:53])[C:50]([OH:52])=[O:51]>CCOCC.C(O)C>[C:49]([OH:54])(=[O:53])[C:50]([OH:52])=[O:51].[OH:1][C:2]([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)([C:43]1[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=1)[CH2:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][N:15]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[CH:8]=1)([C:22]1[CH:27]=[CH:26][C:25]([OH:28])=[C:24]([CH2:29][N:30]2[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]2)[CH:23]=1)[CH3:6]

Participants

5

Reactant 2

HCID 971Oxalic AcidHCID 9875854HCID 9875854, compound

Product 1

HCID 70069774HCID 70069774, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 3283Diethyl EtherSolvent

Procedure

A solution of the compound from Example 2 (0.27 g, 0.42 mmol) in 6 mL of ether was treated with oxalic acid (0.106 g, 0.84 mmol) in 1 mL of ethanol. The white precipitate which formed was collected and washed with 20 mL of ether. The solid obtained was dried under vacuum (P2O5) to give the title compound as a white solid, mp=135-150° C.

Workup

  1. customThe white precipitate which formed
  2. customwas collected
  3. washwashed with 20 mL of ether
  4. customThe solid obtained
  5. dry with materialwas dried under vacuum (P2O5)

Sources & evidence

ORD record
ord-3d233ab7daa74274b46006687b89085b
Source dataset
uspto-grants-2000_09
Patent number
US06124280

Reaction notes

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