Isopropylamine → HCID 10656854, compound

HRID 1954704Notes

Reaction equation

Cl[C:2]1[C:3]2[N:4]([CH:12]=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH:15]([NH2:18])([CH3:17])[CH3:16]>>[CH:15]([NH:18][C:2]1[C:3]2[N:4]([CH:12]=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2)([CH3:17])[CH3:16]

Participants

Reactant 2

HCID 6363Isopropylamine

HCID 107745254-chloroimidazo[1,2-a]quinoxaline

Product 1

HCID 10656854HCID 10656854, compound

Procedure

By reaction of 4-chloroimidazo[1,2-a]quinoxaline (example 1) with isopropylamine according to a procedure that is similar to that followed in example 3 there is obtained 4-isopropylaminoimidazo[1,2-a]quinoxaline. m.p. (DSC)=102.7° C. (onset); IR (KBr): 3230, 2966, 1559 cm-1 ; 1H-NMR (DMSO-d6): δ8.55 (1H,s), 8.2÷7.95 (1H,m), 7.6÷7.4 (2H,m), 7.4÷7.2 (3H,m), 4.5 (1H,m), 1.25 (6H,d); UV (EtOH): λmax =227, 244, 285, 297, 318, 332 nm. Elementary analysis for C13H14N4 (m.w. 226.28): calcd. C 69.00, H 6.23, N 24.76%; found C 69.17, H 6.70, N 25.05%.

Sources & evidence

ORD record: ord-24998950348b4fc5aaf70f69afbf7b14
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06124287

Reaction notes

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