3-Pentanamine → HCID 10801871, compound

HRID 1954705Notes

Reaction equation

Cl[C:2]1[C:3]2[N:4]([C:12]([CH3:15])=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH2:16]([CH:18]([NH2:21])[CH2:19][CH3:20])[CH3:17]>>[CH2:16]([CH:18]([NH:21][C:2]1[C:3]2[N:4]([C:12]([CH3:15])=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH2:19][CH3:20])[CH3:17]

Participants

Reactant 2

HCID 120193-Pentanamine

HCID 10488983HCID 10488983, compound

Product 1

HCID 10801871HCID 10801871, compound

Procedure

By reaction of 4-chloro-1-methylimidazo[1,2-a]quinoxaline (example 2) with 1-ethylpropylamine, according to a procedure that is similar to that followed in example 3 there is obtained 4-(1-ethylpropylamino)-1-methylimidazo[1,2-a] quinoxaline. m.p. (DSC)=75.9° C. (onset); IR (KBr): 3231, 2965, 1546 cm-1 ; 1H-NMR (CDCl3): δ8.0 (1H,dd), 7.7 (1H,dd), 7.4÷7.1 (3H,m), 5.9 (1H,d), 4.2 (1H,m), 2.85 (3H,s), 1.65 (4H,m), 0.95 (6H,t); UV (EtOH): λmax =221, 241, 268, 298, 313 nm. Elementary analysis for C14H20N4 (m.w. 268.36): calcd. C 71.61, H 7.51, N 20.83%; found C 71.12, H 7.53, N 20.79%.

Sources & evidence

ORD record: ord-30698dc375074404a74479c3832a1901
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06124287

Reaction notes

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