Ethanolamine → HCID 10704538, compound

HRID 1954706Notes

Reaction equation

HRID 1954706 reaction equation
Cl[C:2]1[C:3]2[N:4]([CH:12]=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH2:15]([CH2:17][NH2:18])[OH:16]>>[OH:16][CH2:15][CH2:17][NH:18][C:2]1[C:3]2[N:4]([CH:12]=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Participants

3

Reactant 2

HCID 700EthanolamineHCID 107745254-chloroimidazo[1,2-a]quinoxaline

Product 1

HCID 10704538HCID 10704538, compound

Procedure

By reaction of 4-chloroimidazo[1,2-a]quinoxaline (example 1) with ethanolamine according to a procedure that is similar to that followed in example 3 there is obtained 4-(2-hydroxyethylamino)imidazo[1,2-a]quinoxaline. m.p. (DSC)=150.8° C. (onset); IR (KBr): 3312, 1598, 1564 cm-1 ; 1H-NMR (CDCl3 /CD3OD): δ8.2 (1H,s), 8.1÷7.55 (2H,m), 7.55 (1H,s), 7.4÷7.2 (2H,m), 3.8 (4H,s); UV (EtOH): λmax =227, 285, 297, 317, 330 nm. Elementary analysis for C12H12N4 (m.w. 228.25): calcd. C 63.14, H 5.30, N 24.55%; found C 63.16, H 5.40, N 24.99%.

Sources & evidence

ORD record
ord-4ef934b2f563474abc23db6f0cb4b681
Source dataset
uspto-grants-2000_09
Patent number
US06124287

Reaction notes

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