Ethanolamine → HCID 10586250, compound

HRID 1954707Notes

Reaction equation

HRID 1954707 reaction equation
Cl[C:2]1[C:3]2[N:4]([C:12]([CH3:15])=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH2:16]([CH2:18][NH2:19])[OH:17]>>[OH:17][CH2:16][CH2:18][NH:19][C:2]1[C:3]2[N:4]([C:12]([CH3:15])=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Participants

3

Reactant 2

HCID 700EthanolamineHCID 10488983HCID 10488983, compound

Product 1

HCID 10586250HCID 10586250, compound

Procedure

By reaction of 4-chloro-1-methylimidazo[1,2-a]quinoxaline (example 2) with ethanolamine according to a procedure that is similar to that followed in example 3 there is obtained 4-(2-hydroxyethylamino)-1-methyl imidazo[1,2-a]quinoxaline. m.p. (DSC)=173.4° C. (onset); IR (KBr): 3415, 3217, 1558 cm-1 ; 1H-NMR (CDCl3): δ8.0 (1H,dd), 7.7.÷7.2 (3H,m), 7.2 (1H,m), 6.6 (1H,m), 5.3 (1H,sb), 3.85 (3H,m), 2.8 (3H,s); UV (EtOH): λmax =225, 242, 271, 301, 314, 327 nm. Elementary analysis for C13H14N4 (m.w. 242.28): calcd. C 64.45, H 5.82, N 23.12%; found C 64.29, H 5.91, N 23.13%.

Sources & evidence

ORD record
ord-8600305beb3847018e56490343e4befe
Source dataset
uspto-grants-2000_09
Patent number
US06124287

Reaction notes

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