反应详情

By reaction of 4-chloroimidazo[1,2-a]quinoxaline (example 1) with cyclohexylamine, according to a procedure that is similar to that followed in example 3, there is obtained 4-cyclohexylaminoimidazo[1,2-a]quinoxaline. m.p. (DSC)=94.0° C. (onset); IR (KBr): 3227, 2924, 1560 cm-1 ; 1H-NMR (CDCl3): δ7.85 (1H,d, J=2 Hz), 7.8÷7.4 (3H,m), 7.4÷7.1 (2H,m), 6.0 (1H,d), 4.2 (1H,m), 2.3÷1.95 (3H,m), 1.95÷0.9 (6H,m); UV (EtOH): λmax =225, 242, 283, 294, 316, 330 nm. Elementary analysis for C16H18N4 (m.w.266.35): calcd. C 72.15, H 6.81, N 21.03%; found C 72.25, H 7.04, N 21.19%.