Cyclohexylamine → HCID 10568786, compound

HRID 1954722Notes

Reaction equation

Cl[C:2]1[C:3]2[N:4]([CH:14]=[CH:15][N:16]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][C:8]([Cl:12])=[C:7]([Cl:13])[CH:6]=2.[CH:17]1([NH2:23])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH:17]1([NH:23][C:2]2[C:3]3[N:4]([CH:14]=[CH:15][N:16]=3)[C:5]3[C:10]([N:11]=2)=[CH:9][C:8]([Cl:12])=[C:7]([Cl:13])[CH:6]=3)[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

Reactant 2

HCID 7965Cyclohexylamine

HCID 23293697HCID 23293697, compound

Product 1

HCID 10568786HCID 10568786, compound

Procedure

By reacting 4,7,8-trichloroimidazo[1,2-a]quinoxaline example 22 with cyclohexylamine, following a procedure that is similar to that described in example 3, there is obtained 4-cyclohexylamino-7,8-dichloroimidazo[1,2-a] quinoxalin m.p. (DSC)=162.3° C.(onset); IR (KBr): 3332, 2929, 1587, 1550 cm-1 ; 1H-NMR (CDCl3): δ7.8 (2H,m), 7.7 (1H,s), 7.55 (1H,d, J=2 Hz), 6.2 (1H,d), 4.4 (1H,m), 2.3÷1.2 (10H,m); UV (EtOH): λmax =234, 274, 292, 304, 330, 345 nm. Elementary analysis for C16H16Cl2N4 (m.w. 344.25): calcd. C 55.82, H 4.98, N 16.28%; found C 55.83, H 5.00, N 16.31%.

Sources & evidence

ORD record: ord-164c8b93157f4080bf7aeab3a0593b69
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06124287

Reaction notes

Loading…