Dichloromethane → N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-1-(2-hydroxypropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxamide
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([F:23])[cH:18][c:19]([NH2:22])[cH:20][cH:21]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[Cl:68][CH2:69][Cl:70].[OH:24][CH:25]([CH2:26][n:27]1[n:28](-[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:29](=[O:36])[c:30]([C:33](=[O:34])[OH:35])[c:31]1[CH3:32])[CH3:43].[P-:44]([F:45])([F:46])([F:47])([F:48])([F:49])[F:50].[n:51]1([O:52][C:53]([N:54]([CH3:55])[CH3:56])=[N+:57]([CH3:58])[CH3:59])[c:60]2[n:61][cH:62][cH:63][cH:64][c:65]2[n:66][n:67]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([F:23])[cH:18][c:19]([NH:22][C:33]([c:30]4[c:29](=[O:36])[n:28](-[c:37]5[cH:38][cH:39][cH:40][cH:41][cH:42]5)[n:27]([CH2:26][CH:25]([OH:24])[CH3:43])[c:31]4[CH3:32])=[O:34])[cH:20][cH:21]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a869eb197a8645079798fee7f6e9f9d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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