Dichloromethane → HCID 23293602, compound

HRID 1954921Notes

Reaction equation

[CH2:1]([CH:3]1[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)/[C:5](=[CH:13]/[C:14]([OH:16])=O)/[CH2:4]1)[CH3:2].[Cl:17]CCl>>[CH2:1]([CH:3]1[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)/[C:5](=[CH:13]/[C:14]([Cl:17])=[O:16])/[CH2:4]1)[CH3:2]

Participants

Reactant 2

HCID 6344Dichloromethane

HCID 23293599HCID 23293599, compound

Product 1

HCID 23293602HCID 23293602, compound

Procedure

This compound was prepared in an analogous manner to Example 18h with replacement of (E)-2-(6-fluoro-3-methyl-1-indanylidene)acetic acid with (E)-2-(3-ethyl-6-fluoro-1-indanylidene)acetic acid (5.7 g, 25.88 mmol). The product residue was dissolved in dichloromethane and used without purification in Example 26.

Workup

customused without purification in Example 26

Sources & evidence

ORD record: ord-b637a66ea60844b6a48906834a49bf49
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06124284

Reaction notes

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