Ethylamine → N-((6-Chloropyridin-3-yl)methyl)ethanamine

HRID 1954947Notes

Reaction equation

[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8]Cl)=[CH:4][CH:3]=1.[CH2:10]([NH2:12])[CH3:11]>>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][NH:12][CH2:10][CH3:11])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 6341Ethylamine

HCID 1554792-Chloro-5-(chloromethyl)pyridine

Product 1

HCID 11137568N-((6-Chloropyridin-3-yl)methyl)ethanamine

Procedure

Using 6-chloro-3-pyridylmethyl chloride and 70% aqueous ethylamine solution, the reaction according to Reference Example 11 was carried out to give the title compound as a brown oil.

Sources & evidence

ORD record: ord-2f57ef0f3dfb4ccc9a5a02799a56ccd3
Source dataset: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06124297

Reaction notes

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