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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1954953Generated: October 27, 2026

Pyrazine, 2-(chloromethyl)- → N-methyl-1-(pyrazin-2-yl)methanamine

https://huagongshe.com/reaction/1954953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazine, 2-(chloromethyl)-HCID 170169—
ReactantPyridine, 2,6-dichloro-3-(chloromethyl)-HCID 6451791—
ProductN-methyl-1-(pyrazin-2-yl)methanamineHCID 16762521—

Reaction Steps

The reaction according to Reference Example 11 was carried out using 2-chloromethylpyrazine in lieu of 2,6-dichloro-3-pyridylmethyl chloride to give the title compound as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06124297
Source datasetuspto-grants-2000_09
ORD IDord-8e4e41f73043472c8e15604c8c233f22
Source noteuspto-grants-2000_09