HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl chloroformate → 8-[2-(2-Chloroethoxycarbonylamino)-6-methylbenzyloxy]-3-formyl-2-methylimidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl chloroformate | HCID 12305 | — |
| Reactant | 8-(2-Amino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine | HCID 23294167 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 8-[2-(2-Chloroethoxycarbonylamino)-6-methylbenzyloxy]-3-formyl-2-methylimidazo[1,2-a]pyridine | HCID 23294186 | — |
Reaction Steps
According to the procedure indicated in Example 1a, 8-(2-amino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine (2.36 g) and 2-chloroethyl chloroformate (1.3 g) in dichloromethane (150 ml) give the title compound as a brown oil which is used directly for further reaction in 3b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06124313 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-b36515b738204184ae12a56899dde3a4 |
| Source note | uspto-grants-2000_09 |