Water → HCID 23294175, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 3-[2-(3-formyl-2-methylimidazo[1,2-a]pyridin-8-yloxymethyl)-3-methylphenyl]oxazolidin-2-one (1.39 g, 3.8 mmol) and sodium borohydride (0.19 g, 4.75 mmol) in anhydrous ethanol (125 ml) is stirred at RT for 1.5 h. Water (100 ml) is then added, the ethanol is distilled off on a rotary evaporator and the aqueous residue is stirred at 4° C. for 30 min. The precipitate is filtered off, washed with cold water and dried in vacuo. The title compound (1.28 g, 91%) is obtained as a beige solid. M.p. 190-193° C.

Provenance & Evidence