HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-(2-tert-Butoxycarbonylamino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine → 8-(2-Amino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-(2-tert-Butoxycarbonylamino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine | HCID 23294162 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 8-(2-Amino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine | HCID 23294167 | 96% |
Reaction Steps
Starting from 8-(2-tert-butoxycarbonylamino-6-methylbenzyloxy)-3-formyl-2-methylimidazo[1,2-a]pyridine (5.0 g) and trifluoroacetic acid (40 ml) analogously using the process of Example C1 (Method B) gives 3.57 g (96%) of the title compound of m.p. 144-150° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06124313 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-ba786f2ac9ea444981d229e97c1d2a61 |
| Source note | uspto-grants-2000_09 |