Ethanolamine → tert-Butyl 2-(aminomethyl)morpholine-4-carboxylate

HRID 195513Notes

Reaction equation

HRID 195513 reaction equation
[NH2:27][CH2:28][CH2:29][OH:30].[O:1]=[C:2]1[N:3]([CH2:12][CH:13]2[O:14][CH2:15][CH2:16][N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]2)[C:10](=[O:11])[c:5]2[c:4]1[cH:9][cH:8][cH:7][cH:6]2.[OH2:26]>>[NH2:3][CH2:12][CH:13]1[O:14][CH2:15][CH2:16][N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]1

Participants

4

Reactant 3

HCID 700EthanolamineHCID 962WaterHCID 58992660tert-Butyl 2-((1,3-dioxoisoindolin-2-yl)methyl)morpholine-4-carboxylate

Product 1

HCID 19081094tert-Butyl 2-(aminomethyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-37e2000a19b943e191a5ac113d7c2d6e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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