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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1955204Generated: November 2, 2026

4-Cyanopyridine → HCID 23294327, compound

https://huagongshe.com/reaction/1955204

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-CyanopyridineHCID 7506—
Reactant2-BromonaphthaleneHCID 11372—
ReactantButyllithiumHCID 178418339—
ProductHCID 23294327HCID 23294327—

Reaction Steps

4-((2-Naphthyl)methyl)pyridine was prepared from 2-bromonaphthalene, n-BuLi and 4-cyanopyridine in two steps as a yellow solid: mp 66-67° C., 1H NMR (CDCl3) 4.13 (s, 2H), 7.14 (d, J=6.0 Hz, 2H), 7.27 (dd, J=5.7 and 1.8 Hz, 1H), 7.42-7.52 (m, 2H), 7.64 (s, 1H), 7.74-7.86 (m, 3H), 8.51 (dd, 4.8 and 1.5 Hz, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06124323
Source datasetuspto-grants-2000_09
ORD IDord-b4825e64720b4cd389edc9d02b6a6e99
Source noteuspto-grants-2000_09