Potassium Carbonate → HCID 23294333, compound

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The title compound was prepared from 4-((5,6,7,8-tetrahydro-2-naphthyl)methyl)piperidine hydrochloride (250 mg, 940 μmol), 2-(4-fluorophenoxy)ethyl bromide (216 mg, 987 μmol) and K2CO3 (266 mg, 1.93 mmol) as a colorless solid (220 mg): mp 181-183° C.; 1H NMR (CDCl3) 1.60-2.12 (m, 9H), 2.54 (d, J=7.2 Hz, 2H), 2.65-2.81 (m, 6H), 3.20-3.55 (m, 2H), 3.59-3.71 (m, 2H), 4.52 (t, J=4.2 Hz, 2H), 6.77-7.01 (m, 7H), 12.55 (bs, 1H); Anal. Calcd for C24H31ClFNO: C, 71.36; H, 7.74; N, 3.47. Found: C, 71.30; H, 7.78; N, 3.39.

Provenance & Evidence