Aluminium lithium hydride → HCID 23294239, compound

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Reaction Steps

The title compound was prepared from reduction of 1-[2-(2-chloro-4-ethoxycarbonylmethylphenoxy)ethyl]-4-(4-chlorobenzyl)piperidine (450.3 mg, 1.0 mmol) by LiAlH4 (38 mg, 1.0 mmol) as oily product (298 mg). 1H NMR (CD3OD) 1.248 (m, 2 H), 1.374 (s, 1 H), 1.572 (m, 4 H), 2.530 (m, 2 H), 2.677 (m, 1 H), 2.782 (m, 2 H), 2.991-3.139 (m, 4 H), 3.828 (m, 2 H), 4.131 (m, 2 H), 6.868 (m, 1 H), 7.103 (m, 2 H), 7.233 (m, 4 H). HRMS Calcd for C22H2735Cl2NO2 : 407.1435; Found: 407.1427.

Provenance & Evidence