Dimethylformamide → HCID 23295252, compound

Participants

Reaction Conditions

Reaction Steps

20.0 g (0.114 mol) of 2,6-dichlorobenzaldehyde were dissolved in 100 ml of dimethylformamide and, while stirring at -15° C. under nitrogen protective gas, 7.54 g (0.107 mol) of sodium methanethiolate were added. The mixture was stirred at -10 to -15° C. for 5 h and then at room temperature for 12 h. The mixture was taken up in methyl tert-butyl ether, washed with water, dried over sodium sulfate and concentrated under reduced pressure. Yield 19.6 g (92%) of solid.

Provenance & Evidence