HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropyl Ether → HCID 19070831, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropyl Ether | HCID 7914 | — |
| Reactant | m-Tolyl isocyanate | HCID 69303 | — |
| Reactant | 3-amino-1H-1,5-benzodiazepine-2,4(3H,5H)-dione | HCID 21955806 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19070831 | HCID 19070831 | 99.8% |
Reaction Steps
A mixture of 3-amino-1H-1,5-benzodiazepine-2,4(3H,5H)-dione (1.761 g, 9.21 mmol) and m-tolylisocyanate (1.31 g, 10.13 mmol) in dimethylformamide (17 ml) is stirred for 1 hr under ice-cooling. To the reaction mixture is added diisopropyl ether (50 ml) and the resultant crystalline precipitates are filtered off to obtain Compound 5 (2.98 g; yield, 99%). M.p. >300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05776929 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-564b8839f1c442a0976ea40ff2e35e6b |
| Source note | uspto-grants-1998_07 |