1-(Bromoacetyl)pyrrolidine → HCID 22373205, compound

HRID 1955596Notes

Reaction equation

HRID 1955596 reaction equation
[C:1]([O:5][C:6]([NH:8][CH:9]1[C:15](=[O:16])[NH:14][C:13]2[CH:17]=[CH:18][CH:19]=[CH:20][C:12]=2[NH:11][C:10]1=[O:21])=[O:7])([CH3:4])([CH3:3])[CH3:2].[N:22]1([C:27]([CH2:29]Br)=[O:28])[CH2:26][CH2:25][CH2:24][CH2:23]1>>[N:22]1([C:27]([CH2:29][N:14]2[C:13]3[CH:17]=[CH:18][CH:19]=[CH:20][C:12]=3[N:11]([CH2:29][C:27]([N:22]3[CH2:26][CH2:25][CH2:24][CH2:23]3)=[O:28])[C:10](=[O:21])[CH:9]([NH:8][C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])[C:15]2=[O:16])=[O:28])[CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 111061881-(Bromoacetyl)pyrrolidineHCID 19070822HCID 19070822, compound

Product 1

HCID 22373205HCID 22373205, compound

Procedure

Compound 14a is prepared in a manner similar to that used for preparation of Compound 14 h using previously prepared Compound 13 and pyrrolidinocarbonylmethyl bromide.

Workup

  1. customthat used for preparation of Compound 14 h

Sources & evidence

ORD record
ord-1b4bb8a767e54f84ad42322c3324c0d0
Source dataset
uspto-grants-1998_07
Patent number
US05776929

Reaction notes

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