2-(Chloroacetyl)thiophene → HCID 53654234, compound

HRID 1955597Notes

Reaction equation

HRID 1955597 reaction equation
[C:1]([O:5][C:6]([NH:8][CH:9]1[C:15](=[O:16])[NH:14][C:13]2[CH:17]=[CH:18][CH:19]=[CH:20][C:12]=2[NH:11][C:10]1=[O:21])=[O:7])([CH3:4])([CH3:3])[CH3:2].[S:22]1[CH:26]=[CH:25][CH:24]=[C:23]1[C:27]([CH2:29]Cl)=[O:28]>>[S:22]1[CH:26]=[CH:25][CH:24]=[C:23]1[C:27]([CH2:29][N:14]1[C:13]2[CH:17]=[CH:18][CH:19]=[CH:20][C:12]=2[N:11]([CH2:29][C:27]([C:23]2[S:22][CH:26]=[CH:25][CH:24]=2)=[O:28])[C:10](=[O:21])[CH:9]([NH:8][C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])[C:15]1=[O:16])=[O:28]

Participants

3

Reactant 2

HCID 27579252-(Chloroacetyl)thiopheneHCID 19070822HCID 19070822, compound

Product 1

HCID 53654234HCID 53654234, compound

Procedure

Compound 14g is prepared in a manner similar to that used for preparation of Compound 14 h using previously prepared Compound 13 and 2-thienylcarbonylmethyl chloride.

Workup

  1. customthat used for preparation of Compound 14 h

Sources & evidence

ORD record
ord-b546accf488f4a76910f69b4f8f83618
Source dataset
uspto-grants-1998_07
Patent number
US05776929

Reaction notes

Loading…