HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 3-(4-(Benzyloxy)phenyl)pentanedioic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Benzaldehyde, 4-(phenylmethoxy)- | HCID 78109 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Product | 3-(4-(Benzyloxy)phenyl)pentanedioic acid | HCID 27281582 | — |
Reaction Steps
4-Benzyloxybenzaldehyde (50.0 g, Aldrich), ethyl acetoacetate (61.31 g, Aldrich), and piperidine (4.01 lg) were reacted together overnight. The resulting mixture was refluxed for 3-4 hours with ethanol (400 ml) and sodium methoxide (63.63 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05776951 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-93fbbd748e0546a3adc53c6cc49e7f46 |
| Source note | uspto-grants-1998_07 |