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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1955664Generated: November 1, 2026

1-Aminoindole → N-(3-Methyl-4-pyridinyl)-1H-indol-1-amine

https://huagongshe.com/reaction/1955664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-AminoindoleHCID 643221—
Reactant4-Chloro-3-methylpyridine hydrochlorideHCID 16217655—
SolventIsopropanolHCID 3776—
ProductN-(3-Methyl-4-pyridinyl)-1H-indol-1-amineHCID 14988268—

Reaction Steps

The title compound was prepared from 1H-indol-1-amine and 4-chloro-3-methylpyridine hydrochloride in isopropanol at 90° C. for 6 hours in substantially the same manner as in Example 17, m.p. 78°-80° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05776955
Source datasetuspto-grants-1998_07
ORD IDord-25a10412f9404ac7932ca5dd590b4abe
Source noteuspto-grants-1998_07