反应详情

温度

70 °C

To a suspension of sodium benzenesulfinate (10 g, 60.9 mmol) and benzyl carbamate (9.21 g, 60.9 mmol) in water (40 mL) was added hydrocinnamaldehyde (8.8 mL, 67 mmol) in formic acid (10 mL). The mixture was heated at 70° C. for 1 hour, then permitted to cool to room temperature overnight. The product crystallized out; it was filtered and recrystallized from hot isopropanol, giving 23 g (100%) yield. TLC: (30% ethyl acetate/hexane) Rf =0.37.

1. temperatureto cool to room temperature overnight
2. customThe product crystallized out
3. filtrationit was filtered
4. customrecrystallized from hot isopropanol
5. customgiving 23 g (100%)
6. customyield