Tetrabutylammonium permanganate → HCID 19072511, compound

HRID 1955743Notes

Reaction equation

HRID 1955743 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([CH:20]([CH:28]3[CH2:32][CH2:31][CH2:30][CH2:29]3)[C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])=[CH:16][CH:15]=2)[C:7]([CH:11]=[O:12])=[C:8]([Cl:10])[N:9]=1)[CH2:2][CH2:3][CH3:4].[Mn]([O-])(=O)(=O)=[O:34].C([N+](CCCC)(CCCC)CCCC)CCC>>[CH2:1]([C:5]1[N:6]([CH2:13][C:14]2[CH:15]=[CH:16][C:17]([CH:20]([CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])=[CH:18][CH:19]=2)[C:7]([C:11]([OH:34])=[O:12])=[C:8]([Cl:10])[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 11760202Tetrabutylammonium permanganateHCID 15225591tert-Butyl 2-[4-(2-butyl-4-chloro-5-formyl-imidazol-1-yl-methyl)phenyl]-2-cyclopentylacetate

Product 1

HCID 19072511HCID 19072511, compound

Procedure

6.9 g (15 mmol) of the compound from Example I are oxidised with tetrabutylammonium permanganate analogously to Example XCV. The product is recrystallised from ethyl acetate/petroleum ether (1:1).

Workup

  1. customThe product is recrystallised from ethyl acetate/petroleum ether (1:1)

Sources & evidence

ORD record
ord-8d936c99c85149fc9d5b99416bcab7e9
Source dataset
uspto-grants-1998_07
Patent number
US05776964

Reaction notes

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