Hydroxyamine hydrochloride → HCID 22617350, compound

Participants

Reaction Steps

Methyl 2-benzothiazolecarbodithioate (37 g, 0.16 mol) was converted to 1,4,2-oxathiazine using hydroxylamine hydrochloride (13.2 g) and triethylamine (33 ml) as described in Example 4. The ethyl acetate extract of the product was washed successively with diluted hydrochloric acid (2N), water, 5% sodium hydroxide and water. Evaporation of the solvent left a solid residue which was recrystallized from ethanol/ethyl acetate to 5,6-dihydro-3-(2-benzothiazolyl)-1,4,2-oxathiazine (18.0 g, mp 150°-151° C.) Found C 50.68, H 3.27, N 11.78, C10 H8N2OS2 requires C 50.85, H 3.39, N 11.80.

Provenance & Evidence