Phosphine → HCID 70290517, compound

HRID 1956004Notes

Reaction equation

HRID 1956004 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8](Br)[CH:7]=[CH:6]2.[CH2:14]1[CH2:21][O:20][CH2:19][CH:16]([CH:17]=[CH2:18])[O:15]1.P>[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:18]=[CH:17][CH:16]1[O:15][CH2:14][CH2:21][O:20][CH2:19]1)[CH:7]=[CH:6]2

Participants

5

Reactant 3

HCID 24404PhosphineHCID 787862-Bromo-6-methoxynaphthaleneHCID 139779412-Ethenyl-1,4-dioxane

Product 1

HCID 70290517HCID 70290517, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

It has now been found that, by reacting 6-methoxy-2-bromonaphthalene with 3-ethylenedioxybutene (II) in the presence of a bivalent palladium salt and a phosphine, the reaction takes place extremely rapidly without operating under pressure and the 6-methoxy-2-(3-ethylenedioxybuten-1-yl)naphthalene (III) is obtained in optimum yields.

Sources & evidence

ORD record
ord-94401c28174440da97bf2f95dab12c6f
Source dataset
uspto-grants-1998_07
Patent number
US05777170

Reaction notes

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