p-Toluenesulfonic acid → HCID 67626164, compound

Participants

Reaction Steps

In a reactor equipped with a stirrer and a thermometer., 5-nonenyl-2-[4-(6-tetrahydropyranyloxy-1-heptyl)phenyl]-pyrimidine, p-toluenesulfonic acid and methanol are charged and reacted at room temperature for 2 hours. Then, the reaction mixture is extracted with toluene and the extract is washed with water and evaporated under reduced pressure. A resulting residue is purified by silica gel column chromatography to obtain 5-nonenyl-2-[4-(6-hydroxy-1-heptyl)phenyl]pyrimidine

Provenance & Evidence