HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 1-Indan-1-yl-piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 1-Indanone | HCID 6735 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Catalyst | Titanium isopropoxide | HCID 11026 | — |
| Product | 1-Indan-1-yl-piperazine | HCID 10845802 | 37.1% |
Reaction Steps
Piperazine (17.2 g, 0.2 mol), indan-1-one (2.6 g, 20 mmol), titanium(IV) isopropoxide (13.3 ml, 40 mmol) and sodium borohydride (3.6 g, 95 mmol) were reacted by Method A to give the product (1.5 g, 37.1%). The crude product was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780470 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-482028b360554e6bbe6d6b4b1317bbc8 |
| Source note | uspto-grants-1998_07 |