HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-1-Indanone → 1-(2-Methylpropionyl)-4-(6-methoxy-indan-1-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-1-Indanone | HCID 334036 | — |
| Reactant | 2-Methyl-1-(piperazin-1-yl)propan-1-one | HCID 2761409 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Catalyst | Titanium isopropoxide | HCID 11026 | — |
| Product | 1-(2-Methylpropionyl)-4-(6-methoxy-indan-1-yl)piperazine | HCID 22375372 | — |
Reaction Steps
The title compound was prepared by the above procedure using 6-methoxy-1-indanone (3.2 g, 20 mmol), 1-(2-methylpropionyl)piperazine (3.0 g, 20 mmol), titanium(IV) isopropoxide (8 mL, 24 mmol) and sodium borohydride (2.7 g, 67 mmol) to give 2.2 g of product as the fumarate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780470 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-010d0fcb2a21446192f78da67184b117 |
| Source note | uspto-grants-1998_07 |