1-(2-Phenoxyphenyl)piperazine → 1-[(5-Ethyl-2-methoxy-6-methylpyridin-3-yl)aminocarbony]-4-(2-phenoxyphenyl)piperazine
Reaction equation
C1(O[C:8](=[O:21])[NH:9][C:10]2[C:11]([O:19][CH3:20])=[N:12][C:13]([CH3:18])=[C:14]([CH2:16][CH3:17])[CH:15]=2)C=CC=CC=1.[O:22]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[N:35]1[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:16]([C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:38]2[CH2:39][CH2:40][N:35]([C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=3[O:22][C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH2:36][CH2:37]2)=[O:21])[C:11]([O:19][CH3:20])=[N:12][C:13]=1[CH3:18])[CH3:17]Participants
3
Procedure
Phenyl-N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate and 1-(2-phenoxyphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.
Sources & evidence
- ORD record
- ord-4ef7e7a82eda4d6883dc3b5ca0e5e382
- Source dataset
- uspto-grants-1998_07
- Patent number
- US05780472
Reaction notes
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